Cinchonine
Cinchonine is a naturally occurring Cinchona alkaloid widely utilized as a critical building block in pharmaceutical synthesis and chiral chemistry. It serves as a highly effective chiral auxiliary and resolving agent, enabling the separation of racemic mixtures into pure enantiomers for high-value drug development.
Functioning as a pseudo-enantiomer of cinchonidine, this compound acts as a versatile organocatalyst in asymmetric synthesis reactions, including phase-transfer catalysis. Its reliable stereochemical control makes it indispensable for producing complex Active Pharmaceutical Ingredients (APIs) and fine chemical intermediates.
Supplied as a white crystalline powder, our Cinchonine meets rigorous industry standards for assay purity and chemical stability. It is strictly tested to ensure low impurity profiles, making it suitable for sensitive laboratory research and industrial-scale manufacturing processes.
Cinchonine
- Chiral Resolution: Used extensively as a resolving agent to separate optical isomers in the production of enantiomerically pure organic acids and chiral drugs.
- Asymmetric Catalysis: Acts as a phase-transfer catalyst in organic synthesis for alkylation, Michael additions, and hydroxylation reactions.
- Pharmaceutical Intermediate: Serves as a precursor in the synthesis of specific antimalarial drugs and other therapeutic alkaloid derivatives.
- Analytical Chemistry: Utilized as a reagent for the gravimetric determination of bismuth and the detection of fluorides in laboratory settings.
Cinchonine is biologically active and must be handled with care. It may cause skin irritation, serious eye irritation, and respiratory sensitization upon inhalation. Prolonged exposure can lead to photosensitivity. Personnel must utilize chemical-resistant gloves, safety goggles, and an approved dust respirator or extraction system to prevent ingestion or inhalation.
• 25 kg Fiber Drums
• 25 kg Multi-ply Paper Bags
• 50 kg Kegs
• Custom laboratory quantities (upon request)
