1,2-Benzenedicarboxaldehyde
OPA, o-Phthalaldehyde, Phthaldialdehyde.
- CAS
- 643-79-8
- EC
- 211-402-2
- Sectors
- Pharma & Healthcare
1,2-Benzenedicarboxaldehyde (CAS 643-79-8), also known as o-Phthalaldehyde or OPA, is a yellow, light-sensitive dialdehyde supplied as a Technical Grade powder and used as a high-level medical disinfectant and a fluorometric analytical reagent for amino acids. It is a yellow crystalline solid that provides rapid sterilization against a wide range of bacteria and spores. Its high sensitivity and reactivity make it a staple in laboratory diagnostics and biochemical research. In medical settings, OPA is a preferred alternative to glutaraldehyde for the disinfection of endoscopes and other heat-sensitive instruments. It offers a faster kill time and improved material compatibility for high-turnover medical equipment.
Typical Properties
| Molecular formula | C8H6O2 |
|---|---|
| Molecular weight | 134.13 g/mol |
| Appearance | Light yellow powder |
| Form | powder |
| Color | yellow |
| Melting point | 56 °C |
| Boiling point | 83-84 °C (0.7501 mmHg) |
| Density | 1.13 |
| Water solubility | soluble |
| Flash point | >230 °F |
| pH | 7 (53g/l, H2O, 20°C) |
| GHS signal word | Danger · Flammable, Corrosive, Acute toxicity, Irritant / harmful, Health hazard, Environmental hazard |
| HS code | 29122900 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
1,2-Benzenedicarboxaldehyde
Applications
- Medical Sterilization: Used as a 0.55% solution for the high-level disinfection of surgical and diagnostic instruments.
- Diagnostic Reagent: Employed in pre-column derivation for HPLC analysis of primary amines and amino acids.
- Chemical Intermediate: Acts as a precursor in the synthesis of specialized heterocyclic compounds and dyes.
Safety & Risks
Classified as Toxic if Swallowed and a Skin Sensitizer. Can cause Severe Respiratory Irritation. Use in a Fume Hood with Respirator and Gloves.
Packaging
25 kg Drums, 1 kg Glass Bottles, and specialized darkened containers to prevent light degradation.