Triclosan
TCS, 2,4,4'-Trichloro-2'-hydroxydiphenyl ether.
- CAS
- 3380-34-5
- EC
- 222-182-2
- Sectors
- Personal Care & Cosmetics, Pharma & Healthcare, Textiles, Leather & Paper
Triclosan (CAS 3380-34-5) is a chlorinated diphenyl ether with broad-spectrum antibacterial and antifungal activity that appears as a colorless or white crystalline powder, is effective at low concentrations against Gram-positive and Gram-negative bacteria, and is used in clinical disinfection, oral care and industrial hygiene. It functions as a biocide by inhibiting fatty acid synthesis in bacterial cells, preventing their growth and reproduction. The chemical is highly substantive to skin , providing long-lasting antimicrobial protection even after rinsing in soap and detergent applications. Despite regulatory shifts in some regions for consumer soaps, it remains a critical Specialty Chemical in surgical scrubs and clinical disinfection protocols. Its 99% Purity ensures compliance with rigorous pharmaceutical standards for topical antiseptic formulations.
Typical Properties
| Molecular formula | C12H7Cl3O2 |
|---|---|
| Molecular weight | 289.54 g/mol |
| Appearance | Solid |
| Form | Solid |
| Color | colorless or white |
| Melting point | 54-57.3 °C |
| Boiling point | 374 °C |
| Density | 1.356 g/cm³ |
| GHS signal word | Danger · Acute toxicity, Irritant / harmful, Environmental hazard |
| HS code | 29095000 |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Triclosan
Applications
- Clinical Disinfection: Used as the active ingredient in surgical hand scrubs and hospital-grade soaps to minimize the risk of cross-contamination.
- Oral Care: Incorporated into specialized toothpastes to combat plaque and gingivitis due to its effective antimicrobial action in the oral cavity.
- Industrial Hygiene: Applied as a preservative in textiles and plastics to prevent the growth of mold and mildew in high-moisture environments.
Safety & Risks
Classified as a Skin and Eye Irritant and is Very Toxic to Aquatic Life with long-lasting effects. Use Dust Protection, Protective Clothing, and follow strict hazardous waste disposal guidelines.
Packaging
Typically supplied in 25 kg Fiber Drums with double PE lining to prevent moisture ingress and dust migration.