Alpha-GPC (L-Alpha-Glycerylphosphorylcholine)
choline alfoscerate, CHOLINE ALFOSCERATE, choline alphoscerate, Choline glycerophosphate
- CAS
- 28319-77-9
- EC
- 248-962-2
- Sectors
- Nutraceuticals & Supplements, Food & Nutrition
Alpha-GPC (L-Alpha-Glycerylphosphorylcholine) (CAS 28319-77-9) is a choline-containing phospholipid and a naturally occurring choline precursor that appears as a white to off-white waxy solid and is used as a bioavailable choline source in food supplement and functional food formulations. It presents as a white to off-white waxy solid, melting point 142.5 °C, boiling point 480 °C at 101 325 Pa, and is highly water-soluble at 1000 g/L (25 °C). It serves as a bioavailable source of choline, a vitamin-like nutrient involved in phospholipid metabolism and neurotransmitter synthesis, and is widely used as an active ingredient in food supplement and functional food formulations.
Typical Properties
| Molecular formula | C8H20NO6P |
|---|---|
| Molecular weight | 378.4 g/mol |
| Appearance | White waxy solid |
| Form | solid |
| Color | White to Off-White |
| Melting point | 142.5 °C |
| Boiling point | 480°C[at 101 325 Pa] |
| Water solubility | 1000g/L at 25°C |
| Flash point | 11 °C |
| HS code | 29239000 |
| Grades available | Food Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Alpha-GPC (L-Alpha-Glycerylphosphorylcholine)
Applications
- Nutraceuticals & Supplements: high-bioavailability choline source for cognitive support
- Sports Nutrition: choline donor in pre-workout performance formulations
- Pharmaceuticals: active ingredient or excipient in choline-supplementation preparations
- Food & Nutrition: choline contributor in functional foods and fortified beverages
- Cosmetics: low-level phospholipid-based skin-conditioning topical ingredient
Safety & Risks
Not classified as hazardous under GHS. Low acute toxicity profile. Avoid eye contact; use standard PPE when handling bulk material. Store in a cool, dry location away from moisture and direct light.
Packaging
Supplied in 25 kg fibre drums or cartons; 1 kg and 5 kg options available for small lots. Store sealed in cool, dry conditions.