Chlorobutyric Acid
4-CBA, gamma-Chlorobutyric acid, 4-Chlorobutanoic acid.
- CAS
- 627-00-9
- EC
- 210-975-2
- Sectors
- Pharma & Healthcare, Plastics & Polymers
4-Chlorobutyric Acid is a specialized carboxylic acid used as a versatile organic intermediate. It provides a reactive four-carbon chain with a terminal halogen, making it ideal for cyclization reactions.
It is the primary precursor for the production of gamma-butyrolactone (GBL), a vital industrial solvent. Its high purity is critical for manufacturers in the pharmaceutical sector developing complex heterocyclic compounds.
The compound is also utilized as a modifying agent in the production of performance polymers and plasticizers. Its chemical versatility allows for the creation of various esters used in heavy industrial research.
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Chlorobutyric Acid
Applications
- Pharma Intermediates: Used to synthesize medications targeting the central nervous system and other therapeutic areas.
- GBL Production: Acts as the direct chemical precursor for gamma-butyrolactone and pyrrolidone derivatives.
- Polymer Modification: Utilized in the synthesis of specialty plasticizers to improve resin flexibility.
Safety & Risks
Causes severe skin burns and eye damage. Harmful if swallowed. Handling requires acid-resistant PPE, including nitrile gloves, goggles, and aprons.
Packaging
200 kg plastic drums; 1000L IBC totes for large-scale industrial consumers.