Glycyrrhizin
Glycyrrhizic Acid, Licorice Extract, GA.
- CAS
- 1405-86-3
- EC
- 215-785-7
- Sectors
- Food & Nutrition, Pharma & Healthcare, Personal Care & Cosmetics
Glycyrrhizin (CAS 1405-86-3) is a high-purity triterpenoid saponin extracted from Glycyrrhiza glabra roots, supplied as a white to light yellow solid, and used as a natural sweetener about 50 times more potent than sucrose, as an active pharmaceutical ingredient in liver-support medicines, and as a soothing agent in cosmetic creams. In Food Grade form, it serves as a natural sweetener with a potency 50 times greater than sucrose, characterized by a lingering aftertaste.
This Pharmaceutical Grade compound possesses significant anti-inflammatory and hepatoprotective properties, making it a key component in liver-support medications. Its surfactant-like properties also allow it to stabilize emulsions and foams in various industrial formulations.
In cosmetics, it is highly valued for its skin-soothing and anti-redness effects, often used to treat sensitive or irritated skin. As a versatile Specialty Chemical, it provides multifunctional benefits across flavor, health, and topical care sectors.
Typical Properties
| Molecular formula | C42H62O16 |
|---|---|
| Molecular weight | 822.93 g/mol |
| Form | Solid |
| Color | White to Light Yellow |
| Odor | at 100.00 %. mild spicy |
| Melting point | 220 °C (decomp) |
| HS code | 29389000 |
| Grades available | Food Grade, Pharma Grade, Cosmetic Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Glycyrrhizin
Applications
- Liver Health Drugs: Used as an active pharmaceutical ingredient (API) for treating chronic hepatitis and liver inflammatory conditions.
- Confectionery Flavoring: Acts as a sweetening and flavoring agent in licorice-based sweets and herbal teas.
- Soothing Cosmetics: Integrated into anti-inflammatory creams to reduce redness and irritation in sensitive skin types.
Safety & Risks
Chronic overconsumption can lead to Hypertension and electrolyte imbalance. Use Dust Masks and Safety Glasses to avoid inhalation during industrial processing.
Packaging
25 kg Fiber Drums with PE inner liners; 1 kg Foil Bags for pilot-scale use.