Hydroxypropyl Cellulose
HPC, Hydroxypropylcellulose, Oxypropylated Cellulose.
- CAS
- 9004-64-2
- EC
- 618-388-0
- Sectors
- Pharma & Healthcare, Personal Care & Cosmetics
Hydroxypropyl Cellulose (CAS 9004-64-2) is a non-ionic cellulose ether supplied as a white powder that dissolves in both water and organic solvents, and it serves as a tablet binder, film coating and thickener in pharmaceutical and cosmetic formulations. This Pharmaceutical Grade polymer is an essential binder for tablet production, providing exceptional mechanical strength and flexibility.
It acts as a high-efficiency Technical Grade thickener and film-former in topical gels and cosmetic emulsions. Its thermoplastic properties allow for use in specialized melt-extrusion processes for advanced drug delivery systems.
The product is valued for its surface activity, which aids in stabilizing emulsions and foams in personal care formulations. It provides a smooth, non-tacky feel and creates clear, tough protective films upon drying.
Typical Properties
| Molecular weight | 59.0871 g/mol |
|---|---|
| Appearance | white powder |
| Form | powder |
| Color | White to light cream |
| Odor | at 100.00?%. odorless |
| Melting point | 155.10 °C |
| Density | 0.50 g/cm³ |
| pH | pH (20g/l, 25°C) : 5.0~7.5 |
| HS code | 39129000 |
| Grades available | Pharma Grade, Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Hydroxypropyl Cellulose
Applications
- Tablet Binding: Used in dry and wet granulation to ensure high tablet hardness and low friability in solid dosage forms.
- Film Coating: Applied as a moisture barrier and aesthetic coating for tablets, offering high flexibility and crack resistance.
- Ophthalmic Lubrication: Functions as a thickening agent in artificial tears to increase ocular residence time and patient comfort.
Safety & Risks
Chemically inert and non-toxic. Fine dust may form explosive mixtures with air. Use PPE including Goggles and Safety Gloves. Hazard Classifications: Not a hazardous substance.
Packaging
Standard 25 kg Fiber Drums with moisture-resistant PE liners.