Hydroxypropyl Cellulose

HPC, Hydroxypropylcellulose, Oxypropylated Cellulose.

CAS
9004-64-2
EC
618-388-0
Sectors
Pharma & Healthcare, Personal Care & Cosmetics

Hydroxypropyl Cellulose (CAS 9004-64-2) is a non-ionic cellulose ether supplied as a white powder that dissolves in both water and organic solvents, and it serves as a tablet binder, film coating and thickener in pharmaceutical and cosmetic formulations. This Pharmaceutical Grade polymer is an essential binder for tablet production, providing exceptional mechanical strength and flexibility.

It acts as a high-efficiency Technical Grade thickener and film-former in topical gels and cosmetic emulsions. Its thermoplastic properties allow for use in specialized melt-extrusion processes for advanced drug delivery systems.

The product is valued for its surface activity, which aids in stabilizing emulsions and foams in personal care formulations. It provides a smooth, non-tacky feel and creates clear, tough protective films upon drying.

Typical Properties

Molecular weight59.0871 g/mol
Appearancewhite powder
Formpowder
ColorWhite to light cream
Odorat 100.00?%. odorless
Melting point155.10 °C
Density0.50 g/cm³
pHpH (20g/l, 25°C) : 5.0~7.5
HS code39129000
Grades availablePharma Grade, Technical Grade

Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.

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Hydroxypropyl Cellulose

Applications
  • Tablet Binding: Used in dry and wet granulation to ensure high tablet hardness and low friability in solid dosage forms.
  • Film Coating: Applied as a moisture barrier and aesthetic coating for tablets, offering high flexibility and crack resistance.
  • Ophthalmic Lubrication: Functions as a thickening agent in artificial tears to increase ocular residence time and patient comfort.
Safety & Risks

Chemically inert and non-toxic. Fine dust may form explosive mixtures with air. Use PPE including Goggles and Safety Gloves. Hazard Classifications: Not a hazardous substance.

Packaging

Standard 25 kg Fiber Drums with moisture-resistant PE liners.