Hydroxypropyl Methyl Cellulose Phthalate

HPMCP, Hypromellose Phthalate

CAS
9050-31-1
EC
618-567-3
Sectors
Pharma & Healthcare

Hydroxypropyl Methyl Cellulose Phthalate (CAS 9050-31-1) is a white to off-white, free-flowing cellulose ester containing phthalyl and hydroxypropyl groups, supplied as flakes or granules and used in pharmaceutical enteric coatings for acid resistance and targeted intestinal drug release. It is insoluble in water but soluble in alkaline or organic solvent systems.

Typical Properties

Molecular weight240.304 g/mol
AppearanceWhite to off-white free-flowing flakes or granules
Formneat
Melting point145 °C (approx)
Density1.277 g/cm³
GHS signal wordDanger · Acute toxicity, Irritant / harmful
HS code39129090

Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.

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Hydroxypropyl Methyl Cellulose Phthalate

Applications

Used in pharmaceutical enteric coatings for acid resistance and targeted intestinal drug release. Also serves as a film-forming polymer in controlled-release formulations.

Safety & Risks

Non-toxic and stable; avoid inhalation of fine dust. Keep away from high humidity and direct heat.

Packaging

Delivered in 25 kg paper bags with PE liners. Store sealed in cool, dry, and ventilated areas.