p-Toluenesulfonamide
PTSA, 4-Methylbenzenesulfonamide, p-Toluenesulphonamide, Tosylamide
- CAS
- 70-55-3
- EC
- 200-741-1
- Sectors
- Plastics & Polymers, Pharma & Healthcare, Water & Wastewater Treatment
p-Toluenesulfonamide (CAS 70-55-3) is a white crystalline sulfonamide powder supplied as a Technical Grade solid plasticizer and intermediate that improves flexibility, impact resistance and surface gloss in melamine, urea-formaldehyde, phenolic and amino resin systems, and serves as an organic building block for sulfonamide-based drugs, disinfectants and chemical blowing agents. It is highly valued for its exceptional thermal stability and seamless compatibility with a wide range of thermosetting resin systems. Its chemical profile ensures uniform solidification and high-quality finishes in industrial molding and coating applications. In the healthcare sector, PTSA acts as a crucial organic building block for the synthesis of antibacterial sulfonamide-based drugs . It also functions as a primary precursor for manufacturing industrial disinfectants and specialized chemical blowing agents.
Typical Properties
| Molecular formula | C7H9NO2S |
|---|---|
| Molecular weight | 171.22 g/mol |
| Appearance | White leaflets. Soluble in alcohol; very slightly soluble inwater.Combustible. |
| Form | Crystalline Powder |
| Color | White |
| Odor | Odorless |
| Melting point | 138.5 °C |
| Boiling point | 214 °C @ Press: 9.98 Torr |
| Water solubility | 0.32 g/100 mL (25 º C) |
| Flash point | 202 °C |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29350090 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
p-Toluenesulfonamide
Applications
- Resin Modification: Acts as an efficient solid plasticizer for phenolic and amino resins to enhance impact resistance and mechanical durability.
- Pharmaceutical Synthesis: Used as a key organic intermediate in the production of sulfonamide-based drugs and active pharmaceutical ingredients (APIs).
- Disinfectant Precursor: Serves as the primary raw material for manufacturing Chloramine-T, widely utilized in industrial water treatment and sanitation.
Safety & Risks
Classified as a skin and eye irritant; contact may cause significant inflammation or respiratory discomfort. Always use nitrile gloves, protective goggles, and a NIOSH-approved dust mask during handling to prevent exposure.
Packaging
- 1 kg / 5 kg Aluminum Foil Bags
- 25 kg Fiber Drums / Woven Bags