Polysorbate 80
Tween 80
- CAS
- 9005-65-6
- EC
- 500-019-9
- Food Code
- E433
- Sectors
- Food & Nutrition, Pharma & Healthcare, Personal Care & Cosmetics
Polysorbate 80, derived from sorbitan monooleate ethoxylated with 20 moles of ethylene oxide, is an amber-colored oily liquid with HLB 15, fully miscible in water and most organic solvents. It provides superior solubilizing capabilities for hydrophobic compounds, maintaining stability in electrolyte-rich solutions and over a broad pH range from 3 to 11.
SoleChem, an ISO 9001:2015 certified chemical supplier based in Türkiye, delivers Polysorbate 80 (CAS 9005-65-6) to customers in more than 40 countries.
Polysorbate 80
Applications
Critical for solubilizing vitamins in oral supplements; in intravenous pharmaceuticals for micelle formation; in hair care products for detangling; in vaccine adjuvants for enhanced delivery; and in agricultural sprays as wetting agents improving pesticide efficacy on foliage.
Safety & Risks
FDA-approved with potential for allergic responses in individuals sensitive to oleic acid derivatives; high doses linked to minor digestive issues. Monitor for ethylene oxide residues per regulatory limits; utilize enclosed systems for handling to reduce vapor exposure and ensure compliance with occupational exposure thresholds.
Packaging
Contained in 200 liter high-density polyethylene totes with tamper-proof seals. Store in ventilated chemical bays, segregated from incompatible substances like peroxides to prevent unintended reactions.