S-Adenosyl-L-Methionine Disulfate Tosylate
SAM-T, Ademetionine Disulfate Tosylate, SAMe Tosylate Disulfate.
- CAS
- 97540-22-2
- EC
- 307-160-0
- Sectors
- Pharma & Healthcare, Nutraceuticals & Supplements
S-Adenosyl-L-Methionine Disulfate Tosylate (CAS 97540-22-2) is a stabilized disulfate tosylate salt of ademetionine, supplied as a white to pale yellow solid, that keeps the methyl donor active in oral solid dosage forms and is used in antidepressant, hepatoprotective and mood support applications. This USP/EP Grade material addresses the stability challenges of the base molecule, allowing for longer storage life.
This complex salt is the preferred choice for manufacturing high-potency tablets and capsules. It maintains a Crystalline Structure that is less prone to degradation, ensuring that the therapeutic methyl donor remains active throughout the product's lifespan.
Our production process guarantees a Purity Level of ≥98%, catering to the rigorous requirements of the pharmaceutical industry. The disulfate tosylate salt configuration is optimized for bioavailability, facilitating efficient metabolic absorption in clinical applications.
Typical Properties
| Molecular formula | C15H23N6O5S.C7H8O3S.H2O4S.HO4S |
|---|---|
| Molecular weight | 768.81 g/mol |
| Form | Solid |
| Color | White to Pale Yellow |
| Melting point | >122°C (dec.) |
| GHS signal word | Danger · Corrosive |
| HS code | 2934990002 |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
S-Adenosyl-L-Methionine Disulfate Tosylate
Applications
- Pharmaceutical Tableting: The primary salt form used in the production of enteric-coated tablets for antidepressant and hepatoprotective medications.
- Nutraceutical Formulation: Employed in high-end mood support and liver health supplements where long-term stability is a critical requirement.
- API Intermediates: Acts as a stable Active Pharmaceutical Ingredient (API) for various therapeutic agents targeting joint and metabolic health.
Safety & Risks
The substance is an Eye and Respiratory Irritant and is significantly more acidic than the base form. Mandatory PPE includes N95 Respiratory Protection, Chemical-Resistant Gloves, and Safety Goggles.
Packaging
Specialized 1 kg or 5 kg Aluminum Foil Bags and 25 kg High-Density Fiber Drums with moisture-barrier liners.