Mannitol
Mannite, Manna Sugar
- CAS
- 69-65-8
- EC
- 200-711-8
- Food Code
- E421
- Sectors
- Pharma & Healthcare, Food & Nutrition, Personal Care & Cosmetics
Mannitol (CAS 69-65-8) is a white crystalline polyol derived from fructose or starch hydrogenation, mildly sweet and chemically stable, and it is used as a pharmaceutical excipient and diuretic, a low-calorie food sweetener, a cosmetic humectant, and a cryoprotectant. It exhibits mild sweetness, low hygroscopicity, and high chemical stability.
Typical Properties
| Molecular formula | C6H14O6 |
|---|---|
| Molecular weight | 182.17 g/mol |
| Appearance | White crystalline powder |
| Form | Crystalline Powder |
| Color | White |
| Odor | at 100.00 %. odorless |
| Melting point | 166-168 °C |
| Boiling point | 290-295 °C @ Press: 3.5 Torr |
| Density | 1.52 g/cm³ @ Temp: 20 °C |
| Water solubility | soluble |
| Flash point | 290-295°C/3.5mm |
| pH | 5.0-6.5 (25°C, 1M in H2O) |
| HS code | 29054300 |
| Grades available | Food Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Mannitol
Applications
Used in pharmaceuticals as a diuretic, bulking agent, and excipient for tablets and lyophilized formulations. In food, it serves as a low-calorie sweetener, and in cosmetics, it acts as a humectant and stabilizer. Industrial uses include cryoprotectants and laboratory reagents.
Safety & Risks
Non-toxic; excessive intake may cause mild laxative effects. Store in dry, moisture-free conditions.
Packaging
Supplied in 25 kg paper bags or fiber drums with PE liners. Store cool, dry, and tightly sealed.