S-Adenosyl-L-Methionine (SAMe)
SAM-e, Ademetionine, AdoMet, S-Adenosylmethionine.
- CAS
- 29908-03-0
- EC
- 249-946-8
- Sectors
- Nutraceuticals & Supplements, Pharma & Healthcare
S-Adenosyl-L-Methionine (SAMe) (CAS 29908-03-0) is an endogenous methyl donor and co-substrate of the methionine cycle, typically presented as a fine crystalline white to yellow powder, and is valued for supporting hormone and neurotransmitter synthesis, glutathione production, and liver, joint, and cognitive supplement formulas. This High Purity compound is a cornerstone of the methionine cycle, acting as a universal methyl donor in cellular metabolism.
In its commercial form, the compound is typically produced as a Fine Crystalline Powder to ensure rapid dissolution and processing. It is highly valued for its role in maintaining lipid membrane fluidity and supporting the production of glutathione, a primary cellular antioxidant.
Due to the molecule's inherent sensitivity to heat and moisture, our Pharmaceutical Grade SAMe is manufactured under strictly controlled environmental conditions. This ensures maximum bioactivity for use in high-end therapeutic applications and clinical-grade nutritional supplements.
Typical Properties
| Molecular formula | C15H22N6O5S |
|---|---|
| Molecular weight | 400.45 g/mol |
| Form | Solid |
| Color | White to Yellow |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29349990 |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
S-Adenosyl-L-Methionine (SAMe)
Applications
• Dietary Supplement Manufacturing: Primary active ingredient for supplements targeting joint health, liver detoxification, and cognitive support.
• Biochemical Research: Utilized as a standard reagent in enzymatic methyltransferase assays and molecular biology studies.
• Metabolic Therapy Formulations: Integrated into specialized nutrition products designed to support the transsulfuration pathway and homocysteine regulation.
Safety & Risks
S-Adenosyl-L-Methionine is generally considered safe but may cause Mild Skin and Eye Irritation. Handling requires standard PPE, including Gloves, Safety Glasses, and Laboratory Coats to ensure occupational safety.
Packaging
Standard industrial formats include 1 kg Vacuum-sealed Foil Bags, 5 kg Tins, and 25 kg Fiber Drums.