Tocopheryl Nicotinate
α-Tocopherol nicotinate, α-Tocopheryl nicotinate, (+/-)-alpha-Tocopherol nicotinate, ALPHA-TOCOPHERYL NICOTINATE
- CAS
- 16676-75-8
- EC
- 605-452-8
- Sectors
- Personal Care & Cosmetics, Nutraceuticals & Supplements, Food & Nutrition
Tocopheryl Nicotinate is an ester of alpha-tocopherol (Vitamin E) and nicotinic acid (Vitamin B3), with molecular formula C₃₅H₅₃NO₃ and molecular weight 535.8 g/mol. It combines the antioxidant activity of the tocopherol moiety with the vasodilatory properties associated with the nicotinate group.
Supplied as a cosmetic-grade material, it is used primarily in topical formulations and nutraceutical applications where a dual-function Vitamin E derivative is required. Physical form and solubility data are available on request from SoleChem.
SoleChem, an ISO 9001:2015 certified chemical supplier based in Türkiye, delivers Tocopheryl Nicotinate (CAS 16676-75-8) to customers in more than 40 countries.
Tocopheryl Nicotinate
Applications
- Personal Care & Cosmetics: Vitamin E ester in creams, serums, lotions.
- Nutraceuticals & Supplements: Softgel/capsule Vitamin E source; not EU Annex II authorised.
- Topical Pharmaceutical: Stable, lipophilic Vitamin E derivative for dermatological preparations.
- Food & Nutrition: Combined tocopherol and nicotinate activity in specialised nutrition.
- Biochemical Research: Reference compound for tocopherol ester bioavailability studies.
Safety & Risks
Not classified as hazardous under GHS. Standard laboratory PPE (gloves, eye protection) recommended during handling. Store in a cool, dry location away from direct light and moisture. No significant handling risks identified.
Packaging
Supplied in 25 kg fibre drums or cartons; 1–5 kg small-lot options available. Store cool, dry, away from light.