Tocopheryl Nicotinate
α-Tocopherol nicotinate, α-Tocopheryl nicotinate, (+/-)-alpha-Tocopherol nicotinate, ALPHA-TOCOPHERYL NICOTINATE
- CAS
- 16676-75-8
- EC
- 605-452-8
- Sectors
- Personal Care & Cosmetics, Nutraceuticals & Supplements, Food & Nutrition
Tocopheryl Nicotinate (CAS 16676-75-8) is the nicotinic acid (Vitamin B3) ester of alpha-tocopherol (Vitamin E), a derivative that pairs tocopherol antioxidant activity with the vasodilatory properties of the nicotinate group and is used mainly in topical formulations and nutraceutical applications. Supplied as a cosmetic-grade material, it is used primarily in topical formulations and nutraceutical applications where a dual-function Vitamin E derivative is required. Physical form and solubility data are available on request from SoleChem.
Typical Properties
| Molecular formula | C35H53NO3 |
|---|---|
| Molecular weight | 535.8 g/mol |
| Grades available | Cosmetic Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Tocopheryl Nicotinate
Applications
- Personal Care & Cosmetics: Vitamin E ester in creams, serums, lotions.
- Nutraceuticals & Supplements: Softgel/capsule Vitamin E source; not EU Annex II authorised.
- Topical Pharmaceutical: Stable, lipophilic Vitamin E derivative for dermatological preparations.
- Food & Nutrition: Combined tocopherol and nicotinate activity in specialised nutrition.
- Biochemical Research: Reference compound for tocopherol ester bioavailability studies.
Safety & Risks
Not classified as hazardous under GHS. Standard laboratory PPE (gloves, eye protection) recommended during handling. Store in a cool, dry location away from direct light and moisture. No significant handling risks identified.
Packaging
Supplied in 25 kg fibre drums or cartons; 1–5 kg small-lot options available. Store cool, dry, away from light.