Vitamin B2 Riboflavin Tetrabutyrate
Riboflavin tetrabutyrate, Vitamin B2 tetrabutyrate, riboflavin butyrate, Hibon
- CAS
- 752-56-7
- EC
- 212-034-5
- Sectors
- Pharma & Healthcare, Animal Nutrition, Nutraceuticals & Supplements
Vitamin B2 Riboflavin Tetrabutyrate (CAS 752-56-7) is a lipophilic tetrabutyric acid ester of riboflavin, a yellow crystalline solid with markedly higher oil solubility than standard riboflavin, and it serves as a fat-soluble Vitamin B2 source for softgel capsules, pharmaceuticals, nutraceuticals, feed and cosmetics. It presents as a yellow crystalline solid, density 1.250 g/cm³, melting point 145–147 °C, with markedly improved oil solubility relative to standard riboflavin.
Also known under the trade name Hibon, this fat-soluble B2 derivative is used where conventional riboflavin cannot be incorporated into lipid-based matrices. It provides a stable, non-discoloring source of Vitamin B2 activity across pharmaceutical, nutraceutical, feed, and cosmetic applications.
Vitamin B2 Riboflavin Tetrabutyrate ships from SoleChem stock in Food Grade and Pharma Grade. Packaging is available in 25 kg drums or cartons for bulk orders, with 1–5 kg containers for small-lot and R&D requirements.
SoleChem supplies customers in Pharma & Healthcare, Animal Nutrition and Nutraceuticals & Supplements under ISO 9001:2015, ISO 22000:2018 for food and nutraceutical products, and GMP+ FSA for feed products. A certificate of analysis (COA) and safety data sheet (SDS) accompany every delivery, and SoleChem completes deliveries to more than 40 countries. Send your specification and required volume for a bulk quote.
Typical Properties
| Molecular formula | C33H44N4O10 |
|---|---|
| Molecular weight | 656.72 g/mol |
| Form | Solid |
| Color | Yellow |
| Melting point | 145-147 °C |
| Density | 1.250 g/cm³ |
| Grades available | Food Grade, Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Applications by Industry
- Pharma & Healthcare
Vitamin B2 Riboflavin Tetrabutyrate supports pharmaceutical formulation as a stable, non-discoloring source of Vitamin B2 activity where conventional riboflavin cannot be incorporated into lipid-based matrices.
- Animal Nutrition
Vitamin B2 Riboflavin Tetrabutyrate fortifies fat-soluble vitamin blends in animal feed and remains stable through pelleting and extrusion processes.
- Nutraceuticals & Supplements
Vitamin B2 Riboflavin Tetrabutyrate is used in nutraceutical softgel capsules, where its oil solubility allows a fat-soluble Vitamin B2 to be carried in lipid-based supplement formats.
Vitamin B2 Riboflavin Tetrabutyrate
Applications
- Pharmaceuticals & Nutraceuticals: Softgel capsules; supports EU energy, skin, vision claims.
- Food Manufacturing: Antioxidant and stabiliser in oils and fat-based spreads.
- Animal Nutrition: Fortifies fat-soluble vitamin blends; stable through pelleting and extrusion.
- Cosmetics: Oil-phase ingredient; stable, non-discolouring topical B2 source.
- Biochemical Research: HPLC-confirmed reference-grade lipophilic riboflavin derivative.
Safety & Risks
Not classified under GHS; low-hazard profile. Avoid prolonged eye and skin contact; use standard PPE. Store away from light and moisture in sealed containers.
Packaging
Available in 25 kg drums or cartons for bulk orders; 1–5 kg containers for small-lot and R&D requirements. Store cool, dry, and away from light.