Vitamin B2 Riboflavin Tetrabutyrate
Riboflavin tetrabutyrate, Vitamin B2 tetrabutyrate, riboflavin butyrate, Hibon
- CAS
- 752-56-7
- EC
- 212-034-5
- Sectors
- Pharma & Healthcare, Animal Nutrition, Nutraceuticals & Supplements
Vitamin B2 Riboflavin Tetrabutyrate (CAS 752-56-7) is a lipophilic tetrabutyric acid ester of riboflavin, a yellow crystalline solid with markedly higher oil solubility than standard riboflavin, and it serves as a fat-soluble Vitamin B2 source for softgel capsules, pharmaceuticals, nutraceuticals, feed and cosmetics. It presents as a yellow crystalline solid, density 1.250 g/cm³, melting point 145–147 °C, with markedly improved oil solubility relative to standard riboflavin.
Also known under the trade name Hibon, this fat-soluble B2 derivative is used where conventional riboflavin cannot be incorporated into lipid-based matrices. It provides a stable, non-discoloring source of Vitamin B2 activity across pharmaceutical, nutraceutical, feed, and cosmetic applications.
Typical Properties
| Molecular formula | C33H44N4O10 |
|---|---|
| Molecular weight | 656.72 g/mol |
| Form | Solid |
| Color | Yellow |
| Melting point | 145-147 °C |
| Density | 1.250 g/cm³ |
| Grades available | Food Grade, Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Vitamin B2 Riboflavin Tetrabutyrate
Applications
- Pharmaceuticals & Nutraceuticals: Softgel capsules; supports EU energy, skin, vision claims.
- Food Manufacturing: Antioxidant and stabiliser in oils and fat-based spreads.
- Animal Nutrition: Fortifies fat-soluble vitamin blends; stable through pelleting and extrusion.
- Cosmetics: Oil-phase ingredient; stable, non-discolouring topical B2 source.
- Biochemical Research: HPLC-confirmed reference-grade lipophilic riboflavin derivative.
Safety & Risks
Not classified under GHS; low-hazard profile. Avoid prolonged eye and skin contact; use standard PPE. Store away from light and moisture in sealed containers.
Packaging
Available in 25 kg drums or cartons for bulk orders; 1–5 kg containers for small-lot and R&D requirements. Store cool, dry, and away from light.