Vitamin K3 Menadione
Menadione, vitamin K3, Vitamin K0, 3-methyl-1,4-naphthoquinone
- CAS
- 58-27-5
- EC
- 200-372-6
- Sectors
- Pharma & Healthcare, Personal Care & Cosmetics
Vitamin K3 Menadione (CAS 58-27-5) is a synthetic naphthoquinone vitamin that occurs as bright yellow crystals, a precursor to bioactive Vitamin K analogues used in pharmaceutical manufacturing and as an antioxidant in topical personal care preparations. It presents as bright yellow crystals with a slight odour, melting point 105–107 °C, boiling point 314 °C, density approximately 1.12 g/cm³, and is practically insoluble in water.
Menadione functions as a synthetic precursor to bioactive Vitamin K analogues and as a controlled-oxidation intermediate. SoleChem supplies it in Food Grade and Pharma Grade (USP/BP) qualities, covering regulated pharmaceutical manufacturing and broader industrial processing sectors.
Vitamin K3 Menadione ships from SoleChem stock in Food Grade and Pharma Grade qualities that serve pharmaceutical manufacturing as well as personal care and cosmetics production. Both grades are available in standard 25 kg fibre drums or cartons, with 1–5 kg cartons offered for small lots.
SoleChem holds ISO 9001:2015 certification and arranges deliveries to more than 40 countries. A certificate of analysis (COA) and safety data sheet (SDS) accompany every delivery, so buyers can check the grade supplied against their specification. Share your target grade, required volume and delivery schedule with the SoleChem team to request a bulk quote.
Typical Properties
| Molecular formula | C11H8O2 |
|---|---|
| Molecular weight | 172.18 g/mol |
| Appearance | Bright yellow crystals |
| Form | crystalline |
| Color | yellow |
| Odor | Slight odor |
| Melting point | 105-107 °C |
| Boiling point | 314 °C |
| Water solubility | INSOLUBLE |
| GHS signal word | Warning · Irritant / harmful, Environmental hazard |
| HS code | 29146900 |
| Grades available | Food Grade, Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Applications by Industry
- Pharma & Healthcare
Vitamin K3 Menadione supports pharmaceutical manufacturing as a synthetic intermediate in Vitamin K analogue production, with Pharma Grade material meeting USP and BP specifications.
- Personal Care & Cosmetics
Vitamin K3 Menadione acts as an antioxidant ingredient in topical skin-conditioning preparations, supporting personal care and cosmetics formulators.
Vitamin K3 Menadione
Applications
- Pharmaceutical manufacturing: Vitamin K analogue synthesis; USP and BP specification.
- Dietary supplements: EU-authorised claims cover blood clotting and bone maintenance.
- Animal feed: Vitamin K source in livestock and aquaculture premix formulations.
- Personal care and cosmetics: antioxidant ingredient in topical skin-conditioning preparations.
- Textile and paper processing: catalytic agent in dye fixation and oxidative finishing.
Safety & Risks
GHS Warning: H302 (harmful if swallowed), H315/H319 (skin/eye irritation), H317 (skin sensitisation), H335 (respiratory irritation), H400/H410 (very toxic to aquatic life). Wear gloves, eye protection, and respiratory PPE. Keep away from drains and water bodies. Store cool, dry, away from light.
Packaging
Supplied in 25 kg fibre drums or cartons; 1–5 kg cartons available for small lots. Store cool, dry, and protected from light.