Calcifediol (25-Hydroxyvitamin D3)
25-Hydroxycholecalciferol, 25-HYDROXYCHOLECALCIFEROL, 25-Hydroxyvitamin D, 25-Hydroxyvitamin D3
- CAS
- 19356-17-3
- EC
- 242-990-9
- Sectors
- Nutraceuticals & Supplements, Food & Nutrition
Calcifediol (25-Hydroxyvitamin D3) is the principal circulating metabolite of cholecalciferol, presenting as a white to off-white crystalline solid with molecular formula C₂₇H₄₄O₂ and molecular weight 400.64 g/mol. Predicted density 1.01 g/cm³, melting point 74–76 °C, boiling point approximately 529 °C. Also identified as 25-hydroxycholecalciferol (CAS 19356-17-3; EC 242-990-9), it carries authorised EU health claims (Reg. 432/2012) covering normal calcium and phosphorus absorption, bone and teeth maintenance, muscle function, immune system function, and cell division.
SoleChem, an ISO 9001:2015 certified chemical supplier based in Türkiye, delivers Calcifediol (25-Hydroxyvitamin D3) (CAS 19356-17-3) to customers in more than 40 countries.
Calcifediol (25-Hydroxyvitamin D3)
Applications
- Pharmaceuticals: active ingredient targeting vitamin D insufficiency in Rx and OTC.
- Nutraceuticals & Supplements: pharma-grade precursor in vitamin D supplement formulations.
- Animal Feed: bioavailable vitamin D source in veterinary and livestock nutrition.
- Food & Nutrition: functional food ingredient requiring calcifediol bioavailability data.
- Cosmetics: topical vitamin D-active ingredient for skin-related applications.
Safety & Risks
GHS classification: Danger. H301, H311, H330 (toxic if swallowed, in contact with skin, or inhaled); H372 (causes organ damage through prolonged exposure). Wear full PPE including respirator, gloves, and eye protection. Store sealed, away from light and moisture, at cool temperatures.
Packaging
Supplied in 25 kg drums or cartons; 1–5 kg small-lot options available. Store cool, dry, and light-protected.