Nattokinase
Subtilisin NAT, NK, Natto Extract, Fibrinolytic Enzyme
- CAS
- 133876-92-3
- EC
- 229-880-6
- Sectors
- Nutraceuticals & Supplements, Food & Nutrition
Nattokinase (CAS 133876-92-3) is a fibrinolytic enzyme isolated and purified from fermented soybeans, supplied as a fine white to off-white powder with standardized activity measured in Fibrin Degradation Units (FU) and used mainly in dietary supplements and functional foods. This high-quality Food Grade ingredient is isolated from Bacillus subtilis cultures to ensure exceptional purity and strictly standardized enzymatic activity.
Renowned for its cardiovascular benefits, the enzyme is characterized by specific Fibrin Degradation Units (FU), acting effectively to support healthy blood flow and circulation. Manufacturers value its high bioavailability and stability, making it ideal for formulation into tablets, capsules, and functional foods.
Supplied as a fine off-white powder, this enzymatic compound is fully water-soluble and compatible with a wide range of pharmaceutical excipients. It undergoes rigorous testing to meet industrial standards for microbiological safety, heavy metal limits, and consistent potency retention.
Typical Properties
| Molecular weight | 517.122 g/mol |
|---|---|
| Form | Solid |
| Color | White to off-white |
| Grades available | Food Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Nattokinase
Applications
- Dietary Supplements: Formulated into capsules and softgels for cardiovascular health support and blood circulation management.
- Functional Foods: Incorporated into health-focused beverages and nutritional bars requiring stable enzymatic activity.
- Pharmaceutical Research: Utilized in the development of natural thrombolytic agents and fibrin-degrading therapies.
- Nutraceutical Blends: Combined with other heart-healthy ingredients like Omega-3s for synergistic vascular support products.
Safety & Risks
While safe for consumption, the industrial handling of concentrated enzymes poses risks of respiratory sensitization and allergic reactions upon inhalation of dust. It is classified as an Irritant to eyes and skin. Personnel must utilize a NIOSH-approved respirator or dust mask, protective gloves, and safety goggles to prevent exposure during batch processing.
Packaging
• 1 kg / 5 kg Aluminum Foil Bags
• 25 kg Fiber Drums (with inner polyethylene liner)
• 25 kg Cartons