Sulbutiamine
arcalion, Arcalion Forte, Bisibuthiamine, Bisibutiamine
- CAS
- 3286-46-2
- EC
- 221-937-3
- Sectors
- Nutraceuticals & Supplements, Food & Nutrition
Sulbutiamine (CAS 3286-46-2) is a synthetic derivative of thiamine (Vitamin B1), supplied as a white to off-white crystalline solid whose lipophilic character gives it greater fat solubility than thiamine, and it is used in nutraceutical and food applications where a bioavailable thiamine source is required. Melting point 144–145 °C, density approximately 1.13 g/cm³; lipophilic character gives it greater fat solubility than thiamine, facilitating membrane permeability. It is available in Food Grade and Pharma Grade.
Typical Properties
| Molecular formula | C32H46N8O6S2 |
|---|---|
| Molecular weight | 702.89 g/mol |
| Form | Solid |
| Color | White to Off-White |
| Melting point | 144-145 °C |
| Grades available | Food Grade, Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Sulbutiamine
Applications
- Nutraceuticals & Supplements: capsules/tablets with authorised EU health claims.
- Food & Nutrition: functional ingredient in lipophilic-thiamine fortified products.
- Pharmaceutical: active ingredient targeting thiamine-related indications.
- Animal Feed: thiamine supplement in compound feed and premixes.
- Cosmetics: topical formulations seeking B-vitamin activity.
Safety & Risks
Not classified as hazardous under GHS. Low acute toxicity profile. Use standard PPE — gloves and eye protection — when handling bulk material. Store away from moisture, heat, and direct light.
Packaging
Supplied in 25 kg fibre drums or cartons; 1 kg and 5 kg options available for small lots. Store cool, dry, away from light.