3-Picoline
3-Methylpyridine, beta-Picoline, m-Picoline
- CAS
- 108-99-6
- EC
- 203-636-9
- Sectors
- Pharma & Healthcare, Agriculture
3-Picoline (CAS 108-99-6) is a methylpyridine isomer, an organic heterocyclic liquid that appears clear yellow and serves as a chemical intermediate in the production of Nicotinic Acid (Vitamin B3) and agrochemical actives used in API manufacturing and crop protection. Known for its high solubility in water and organic solvents, this methylpyridine isomer is the primary feedstock for producing Nicotinic Acid (Vitamin B3) and various agrochemical actives.
This Technical Grade liquid is characterized by its strong odor and high chemical reactivity, making it a preferred precursor for API manufacturing and advanced crop protection solutions.
Typical Properties
| Molecular formula | C6H7N |
|---|---|
| Molecular weight | 93.13 g/mol |
| Form | Liquid |
| Color | Clear yellow |
| Odor | Unpleasant |
| Melting point | -18.1 °C |
| Boiling point | 143-144 °C |
| Density | 0.9566 g/cm³ @ Temp: 20 °C |
| Water solubility | soluble |
| Flash point | 97 °F |
| pH | 10 (100g/l, H2O, 20°C) |
| GHS signal word | Danger · Flammable, Corrosive, Acute toxicity, Irritant / harmful, Health hazard, Environmental hazard |
| HS code | 29333999 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
3-Picoline
Applications
- Vitamin B3 Production: Used as the essential starting material for the oxidation process to synthesize Niacin and Nicotinamide for human and animal nutrition.
- Agrochemical Synthesis: Acts as a critical building block for manufacturing high-efficiency herbicides and insecticides, specifically chlorpyrifos and imidacloprid derivatives.
- Specialty Chemical Intermediate: Utilized as a specialized solvent and reactant in the production of rubber accelerators, textile auxiliaries, and laboratory reagents.
Safety & Risks
3-Picoline is a flammable liquid and vapor that is toxic if swallowed, inhaled, or in contact with skin. It causes severe skin burns and serious eye damage; therefore, operators must wear nitrile gloves, chemical-resistant coveralls, and full-face respiratory protection during handling.
Packaging
- 200 kg Steel Drums
- 1000 kg IBC Totes
- ISO Tanks for bulk industrial supply