2-Picoline
2-Methylpyridine, alpha-Picoline, o-Methylpyridine
- CAS
- 109-06-8
- EC
- 203-643-7
- Sectors
- Pharma & Healthcare, Agriculture
2-Picoline (CAS 109-06-8) is a heterocyclic organic compound and a 2-methyl pyridine derivative supplied as a clear pale yellow liquid in Technical Grade, serving as a primary building block for agrochemical actives such as Nitrapyrin and for pharmaceutical intermediates including APIs. It is a colorless liquid characterized by its high reactivity and solubility in aqueous and organic media.
This Technical Grade chemical is a primary building block for Nitrapyrin and Niacin, essential for modern crop protection and human nutrition. Its role as a pyridine derivative ensures reliability in producing high-value fine chemicals and veterinary products.
The compound provides excellent industrial value as a versatile solvent and reagent in chemical synthesis. Its stability and high-purity specifications meet the rigorous demands of global manufacturing and quality control standards.
Typical Properties
| Molecular formula | C6H7N |
|---|---|
| Molecular weight | 93.13 g/mol |
| Form | Liquid |
| Color | Clear pale yellow |
| Odor | Unpleasant |
| Melting point | -70 °C |
| Boiling point | 128-129 °C |
| Density | 0.9443 g/cm³ @ Temp: 20 °C |
| Water solubility | MISCIBLE |
| Flash point | 79 °F |
| pH | 8.5 (100g/l, H2O, 20°C) |
| GHS signal word | Danger · Flammable, Corrosive, Acute toxicity, Irritant / harmful, Health hazard |
| HS code | 29333999 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
2-Picoline
Applications
- Agrochemical Synthesis: Used as a critical precursor for the production of herbicides and nitrification inhibitors such as Nitrapyrin.
- Pharmaceutical Intermediates: Acts as a fundamental building block for active pharmaceutical ingredients (APIs), including local anesthetics and cardiovascular drugs.
- Vitamin B3 Production: Employed in the commercial synthesis of Nicotinic Acid (Niacin) and Nicotinamide for the food and animal feed sectors.
Safety & Risks
This substance is a flammable liquid and vapor that is toxic if swallowed or inhaled. Contact causes serious eye irritation and skin burns; personnel must use nitrile gloves, respiratory protection, and chemical-resistant goggles at all times.
Packaging
- 190 kg Steel Drums
- 950 kg IBC Tanks
- Bulk ISO Tankers