Allantoin

5-Ureidohydantoin, Glyoxyldiureide, Alcloxa.

CAS
97-59-6
EC
202-592-8
Sectors
Personal Care & Cosmetics, Pharma & Healthcare

Allantoin (CAS 97-59-6) is a naturally occurring compound, also known as 5-ureidohydantoin, supplied as a white, odorless powder that supports skin healing and cell regeneration in cosmetic and pharmaceutical formulations, where it acts as a non-irritating skin-soothing and keratolytic ingredient. It is a High-Purity ingredient that is non-irritating and compatible with most cosmetic actives. It serves as an excellent Technical Grade conditioner in products for sensitive skin. In pharmaceutical applications, it is utilized as a USP Grade active in topical ointments. Its odorless and stable nature makes it ideal for diverse therapeutic formulations and wound care.

Typical Properties

Molecular formulaC4H6N4O3
Molecular weight158.12 g/mol
AppearanceWhite Solid
FormPowder
ColorWhite
Odorodorless, tasteless
Melting point239 °C
Boiling point478 °C
Water solubilitySlightly soluble in water. Freely soluble in alkalis
Flash point230-234°C
GHS signal wordWarning · Irritant / harmful
HS code29332100
Grades availableCosmetic Grade, Pharma Grade, Technical Grade

Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.

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Allantoin

Applications
  • Skincare Products: Included in lotions and after-sun products to reduce irritation and improve smoothness.
  • Wound Care: Used in pharmaceutical ointments to treat minor burns and irritated skin conditions.
  • Oral Hygiene: Added to toothpaste and mouthwashes to soothe gums and promote mucosal health.
Safety & Risks

Considered extremely safe with No Significant Hazards. Use standard PPE, such as Gloves and Safety Glasses, to maintain hygiene during compounding.

Packaging

Available in 25 kg Fiber Drums or custom small-format packaging for specialty use.