Alpha Cyclodextrin
α-CD, Cyclohexapentylose, Schardinger Alpha-Dextrin.
- CAS
- 10016-20-3
- EC
- 233-007-4
- Sectors
- Pharma & Healthcare, Food & Nutrition
Alpha Cyclodextrin (CAS 10016-20-3) is a cyclic oligosaccharide of six glucose units with a hydrophobic cavity for molecular encapsulation; it appears as a white crystalline powder and is used to improve the solubility and bioavailability of hydrophobic actives, stabilize oil-in-water emulsions and mask bitter tastes. This Pharmaceutical Grade excipient significantly increases the aqueous solubility and bioavailability of low-molecular-weight hydrophobic active ingredients.
It is a highly effective Food Grade soluble fiber used to manage dietary fat absorption and stabilize oil-in-water emulsions. The molecule is chemically stable and resistant to enzymatic degradation in the upper gastrointestinal tract, acting as a functional prebiotic.
This High Purity crystalline powder is used to mask odors and bitter tastes in nutritional supplements and oral care products. Its ability to form inclusion complexes makes it essential for protecting sensitive compounds from oxidation and light-induced decay.
Typical Properties
| Molecular formula | C36H60O30 |
|---|---|
| Molecular weight | 972.84 g/mol |
| Appearance | White crystalline powder |
| Form | powder |
| Color | White |
| Odor | at 100.00?%. odorless |
| Melting point | >278 °C (dec.) |
| Density | 1.521 g/cm³ (solid) |
| Water solubility | Soluble in water at 1%(w/v) |
| pH | 5.0-8.0 (1% in solution) |
| HS code | 29400090 |
| Grades available | Pharma Grade, Food Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Alpha Cyclodextrin
Applications
- Bioavailability Enhancement: Encapsulates hydrophobic drug molecules to improve dissolution rates and therapeutic efficacy in pharmaceutical formulations.
- Functional Fiber: Incorporated into beverages and snacks as a soluble fiber to assist in weight management and lipid profile regulation.
- Flavor Masking: Traps volatile or unpleasant flavor molecules to improve the sensory profile of nutritional and medicinal products.
Safety & Risks
Classified as non-hazardous and safe for consumption. Avoid creating airborne dust. Recommended PPE includes Safety Glasses and Protective Gloves. Hazard Classifications: Non-hazardous substance.
Packaging
Standard 25 kg Fiber Drums or 1 kg Vacuum Sealed Bags.