Azelaic Acid
Nonanedioic acid, 1,7-Heptanedicarboxylic acid, AZ.
- CAS
- 123-99-9
- EC
- 204-669-1
- Sectors
- Personal Care & Cosmetics, Pharma & Healthcare, Plastics & Polymers
Azelaic Acid (CAS 123-99-9) is a naturally occurring linear dicarboxylic acid supplied as a white to cream slightly crystalline powder or flake, used as a skin brightening and anti-inflammatory active in dermatological and cosmetic formulations and as a monomer for polymers and esters. This 99% Purity white powder is a powerful anti-inflammatory and antibacterial agent used extensively in dermatological formulations.
In the cosmetic industry, it is a highly sought-after Skin Brightening Agent due to its ability to inhibit tyrosinase. It effectively addresses hyperpigmentation and acne while remaining gentle enough for sensitive skin types in Cosmetic Grade serums.
Industrially, Azelaic Acid serves as a high-performance chemical intermediate. Its Linear Dicarboxylic Structure makes it an essential monomer for producing specialized polymers, high-temperature lubricants, and complex esters used in the rubber industry.
Typical Properties
| Molecular formula | C9H16O4 |
|---|---|
| Molecular weight | 188.22 g/mol |
| Appearance | white to cream solid |
| Form | Slightly Crystalline Powder or Flakes |
| Color | White to slightly yellow |
| Melting point | 106.5 °C |
| Boiling point | 225 °C @ Press: 10 Torr |
| Density | 1.251 g/cm³ |
| Water solubility | 2.4 g/L (20 °C) |
| Flash point | 215 °C |
| pH | 3.5 (1g/l, H2O) |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29171390 |
| Grades available | Cosmetic Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Azelaic Acid
Applications
- Acne and Rosacea Treatments: Active ingredient in pharmaceutical creams (15-20%) used to reduce bacterial growth and inflammation in the pores.
- Hyperpigmentation Serums: Utilized in skincare products to treat melasma and post-inflammatory hyperpigmentation through selective melanocyte inhibition.
- Polymer Manufacturing: Employed in the synthesis of Nylon 6,9 and biodegradable plastics, providing enhanced flexibility and thermal resistance.
Safety & Risks
Generally low toxicity but can cause Mild Skin Irritation and respiratory discomfort if dust is inhaled. Recommended PPE includes Dust Masks, Gloves, and Safety Glasses.
Packaging
25 kg Fiber Drums with moisture-proof liners or 500 kg Bulk Bags.