Calcium Polystyrene Sulfonate
Calcium Polystyrene Sulphonate, Polystyrene Sulfonate Calcium Salt, CPS, Sulfonated Styrene Divinylbenzene Copolymer Calcium Salt
- CAS
- 37286-92-3
- EC
- 218-362-5
- Sectors
- Pharma & Healthcare
Calcium Polystyrene Sulfonate (CAS 37286-92-3) is a cation-exchange resin supplied as a white to light yellow solid powder, a sulfonated styrene divinylbenzene copolymer that exchanges calcium ions for potassium ions in the gut; it serves as the active pharmaceutical ingredient in hyperkalemia treatment and in oral or rectal suspensions. It typically appears as a fine, cream-to-light-brown powder designed for optimal stability in medical formulations.
Functioning effectively as a potassium binder, this polymer works by exchanging calcium ions for potassium ions within the gastrointestinal tract. It is the critical component in treatments for hyperkalemia, ensuring precise electrolyte regulation in patients.
Supplied in Pharmaceutical Grade, this material meets rigorous BP/USP standards for safety and efficacy. It is suitable for compounding into oral suspensions or rectal administration products requiring consistent ion-exchange capacity.
Typical Properties
| Molecular formula | (C8H8O3S)x.xCa |
|---|---|
| Molecular weight | 211.259 g/mol |
| Form | Solid |
| Color | White to light yellow |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Calcium Polystyrene Sulfonate
Applications
- Hyperkalemia Treatment: Used as the primary API in formulations designed to lower high blood potassium levels by binding potassium in the gut.
- Pharmaceutical Suspensions: Acts as a functional polymer in the preparation of oral or rectal suspensions for electrolyte management.
- Ion Exchange Processes: Utilized in specialized pharmaceutical separation and purification processes requiring selective cation exchange.
Safety & Risks
While generally considered low toxicity, handling this powder requires standard Personal Protective Equipment (PPE) including safety goggles and protective gloves. Inhalation of fine particles may cause irritation; therefore, a dust mask or appropriate respiratory protection is recommended during bulk handling to prevent respiratory irritation.
Packaging
• 25 kg Fibre Drums
• 25 kg Multi-ply Bags
• 50 kg Drums