N-Formylmorpholine
4-Formylmorpholine, NFM, 4-Morpholinecarbaldehyde, N-Formyl Morpholine.
- CAS
- 4394-85-8
- EC
- 224-518-3
- Sectors
- Oil, Gas & Energy, Home Care & Industrial Cleaning, Pharma & Healthcare
N-Formylmorpholine (CAS 4394-85-8) is a morpholine-derived formamide specialty solvent that appears as a clear yellow liquid and is used for the extractive distillation of benzene, toluene and xylene from reformate and pyrolysis gasoline, and as a formylating agent and solvent in the production of pharmaceutical and agrochemical intermediates. It acts as a critical agent in the extractive distillation of aromatics, ensuring superior selectivity for Benzene, Toluene, and Xylene (BTX) recovery compared to conventional solvents.
Additionally, this compound serves as a versatile chemical intermediate in the synthesis of pharmaceuticals and agrochemicals, offering reliable consistency for complex organic formulations.
Typical Properties
| Molecular formula | C5H9NO2 |
|---|---|
| Molecular weight | 115.13 g/mol |
| Appearance | CLEAR YELLOW LIQUID |
| Form | Liquid |
| Color | Clear yellow |
| Melting point | 21 °C |
| Boiling point | 234-238 °C |
| Density | 1.145 g/cm³ (liquid) |
| Water solubility | SOLUBLE |
| Flash point | >230 °F |
| pH | 10 (250g/l, H2O, 20°C) |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29349990 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
N-Formylmorpholine
Applications
- Aromatics Extraction:Used as a highly selective solvent for the extractive distillation of high-purity aromatics from reformate or pyrolysis gasoline feedstocks.
- Gas Sweetening: Acts as a physical solvent for the removal of acid gases (such as CO2 and H2S) in natural gas and synthesis gas processing applications.
- Chemical Synthesis: Functions as a formylating agent and solvent in the production of active pharmaceutical ingredients (APIs) and agrochemical intermediates.
- Fiber Processing: Utilized as a specialized spinning solvent in the manufacturing of synthetic fibers within the textile industry.
Safety & Risks
This chemical is classified as an Irritant and may cause specific organ damage (kidneys/liver) through prolonged exposure; distinct care regarding skin contact is required. Operators must utilize full Personal Protective Equipment (PPE), including chemical-resistant gloves, safety goggles, and appropriate respiratory protection in confined areas.
Packaging
• 25 kg Bags
• 200 L Drums
• IBC Totes
• Bulk / ISO Tank