Tetrahydrothiophene
1,4-Butylene Sulfide, THT
- CAS
- 110-01-0
- EC
- 203-728-9
- Sectors
- Oil, Gas & Energy, Mining & Metals, Home Care & Industrial Cleaning
Tetrahydrothiophene (CAS 110-01-0), also known as thiolane, is a cyclic thioalkane and the saturated analog of thiophene that appears as a colorless volatile liquid, used as a process solvent, a fuel gas odorant for natural gas detection and mine safety, and a synthesis reagent. It has a strong unpleasant odor detectable at 0.01 ppm, density of about 1.0 g/cm³, boiling point 119°C, melting point -96°C, and flash point 12°C. Insoluble in water but miscible in ethanol, ether, benzene, and acetone, it is a cyclic thioalkane and saturated analog of thiophene, stable under normal conditions but flammable.
Typical Properties
| Molecular formula | C4H8S |
|---|---|
| Molecular weight | 88.17 g/mol |
| Appearance | colourless liquid |
| Form | liquid |
| Color | Colorless to Almost colorless |
| Odor | Smells of rotting eggs |
| Melting point | -96.16 °C |
| Boiling point | 121.12 °C @ Press: 760 Torr |
| Density | 0.9987 g/cm³ @ Temp: 20 °C |
| Water solubility | immiscible |
| Flash point | 55 °F |
| pH | 7 (H2O, 20°C) |
| GHS signal word | Danger · Flammable, Irritant / harmful |
| HS code | 29349990 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Tetrahydrothiophene
Applications
Used as a solvent in chemical processes, fuel gas odorant for safety in underground mines and natural gas detection, and organocatalyst in reactions like those between enynediones and benzoic acid; reagent for synthesis of epoxides and derivatives; in fire safety stench warning systems and pharmaceutical intermediates.
Safety & Risks
Highly flammable liquid (H225), acute toxicity by ingestion/inhalation/skin (H302, H312, H332), skin/eye irritation (H315, H319), aquatic toxicity (H402, H412); incompatible with acids, diazo/azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides—generates heat/hydrogen gas; chronic exposure may cause organ damage.
Packaging
Packaged in 200L steel drums with epoxy lining for corrosion resistance, or 1L glass bottles for lab use, ensuring vapor-tight seals.