2-Bromothiophene
2-Thienyl bromide, Monobromothiophene.
- CAS
- 1003-09-4
- EC
- 213-699-4
- Sectors
- Pharma & Healthcare, Electronics & Solar PV
2-Bromothiophene (CAS 1003-09-4) is a halogenated thiophene intermediate supplied as a clear, colorless to slightly brownish liquid that carries a reactive bromine site, making it a starting material for functionalized thiophene derivatives used in cross-coupling reactions, organic electronics and pharmaceutical synthesis. It is a High-Purity liquid that serves as a vital starting material for functionalized thiophene derivatives.
This compound is critical for the synthesis of conjugated polymers and small molecules in the organic electronics industry. Its reactive bromine site allows for precise molecular engineering in Suzuki and Stille coupling processes.
In medical chemistry, it is used to introduce the thienyl group into active pharmaceutical ingredients (APIs). It offers the high regioselectivity required for complex multi-step organic synthesis.
2-Bromothiophene is available from SoleChem as Electronic Grade material for customers in the Pharma & Healthcare and Electronics & Solar PV sectors. It ships in 1 kg glass bottles, 25 kg fluorinated drums, or 200 kg steel drums.
SoleChem stocks this intermediate for trial and bulk volumes, holds ISO 9001:2015 certification and delivers to more than 40 countries. SoleChem has supplied chemical products since 2013. A certificate of analysis (COA) and safety data sheet (SDS) accompany every delivery. Share your required quantity and destination to receive a bulk quote.
Typical Properties
| Molecular formula | C4H3BrS |
|---|---|
| Molecular weight | 163.04 g/mol |
| Appearance | colorless to light yellow liqui |
| Form | Liquid |
| Color | Clear colorless to slightly brownish |
| Melting point | <25 °C |
| Boiling point | 53-56 °C @ Press: 18 Torr |
| Density | 1.6284 g/cm³ @ Temp: 20 °C |
| Water solubility | IMMISCIBLE |
| Flash point | 140 °F |
| GHS signal word | Danger · Flammable, Corrosive, Acute toxicity, Irritant / harmful |
| HS code | 29349990 |
| Grades available | Electronic Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Applications by Industry
- Pharma & Healthcare
2-Bromothiophene serves pharmaceutical researchers as a building block for introducing the thienyl group into active pharmaceutical ingredients and for synthesizing cardiovascular and CNS-active agents.
- Electronics & Solar PV
2-Bromothiophene acts as a key building block for thiophene-based semiconductors and organic photovoltaic materials, supporting the development of conjugated polymers and small molecules in organic electronics.
2-Bromothiophene
Applications
- Organic Electronics: A key building block for thiophene-based semiconductors and organic photovoltaic (OPV) materials.
- Drug Discovery: Utilized in the synthesis of cardiovascular medications and central nervous system (CNS) active agents.
- Chemical Research: A standard reagent for exploring aromatic substitution and heterocyclic chemistry in laboratory settings.
Safety & Risks
Classified as Flammable Liquid and Toxic. Causes Serious Eye Irritation and is Harmful if inhaled. Handle under a Fume Hood using Viton Gloves and Safety Goggles.
Packaging
1 kg Glass Bottles, 25 kg Fluorinated Drums, or 200 kg Steel Drums.