4-cyanopyridine

Isonicotinonitrile, 4-Pyridinecarbonitrile, p-Cyanopyridine, 4-CP.

CAS
100-48-1
EC
202-856-7
Sectors
Pharma & Healthcare, Agriculture
4-cyanopyridine is a high-purity heterocyclic intermediate essential for the synthesis of active pharmaceutical ingredients (APIs). It serves as a primary precursor for Isoniazid, a critical medication used in the global treatment of tuberculosis. This crystalline solid is valued for its excellent reactivity in catalytic hydrogenation and hydrolysis reactions. It consistently meets a purity level of ≥99%, ensuring high yields and stability during sensitive industrial chemical synthesis cycles. As a versatile specialty intermediate, it is also utilized in the production of nicotinic acid derivatives and specific agrochemical compounds. Its role as a molecular building block offers efficiency for large-scale organic synthesis operations.

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4-cyanopyridine

Applications
  • API Manufacturing: Acts as the fundamental precursor for the production of Isoniazid and other essential antitubercular drugs.
  • Vitamin Production: Employed as a chemical intermediate in the industrial synthesis of Nicotinic Acid (Vitamin B3) and Nicotinamide.
  • Agrochemical Synthesis: Used in the formulation of specialized pesticides and herbicides that require stable pyridine-based structures.
Safety & Risks
4-cyanopyridine is harmful if swallowed or in contact with skin and acts as a skin and eye irritant. Handling requires a fume hood, nitrile gloves, and ANSI-approved safety goggles to prevent exposure.
Packaging

• 25 kg Fiber Drums

• 50 kg Plastic Drums

• Custom bulk packaging available upon request for industrial scales.