2-cyanopyridine
Picolinonitrile, 2-Pyridinecarbonitrile, Pyridine-2-carbonitrile, 2-CP.
- CAS
- 100-70-9
- EC
- 202-880-3
- Sectors
- Pharma & Healthcare, Agriculture
2-cyanopyridine (CAS 100-70-9) is a heterocyclic nitrile intermediate supplied as a low melting crystalline solid ranging from white to brown, and it is used as a building block for picolinate-based active pharmaceutical ingredients, agrochemical herbicides and pesticides, and Vitamin B3 precursors. Its crystalline solid form ensures stable handling and precise dosing during complex multi-step chemical reactions.
Known for its excellent solubility in organic solvents, this compound serves as a critical precursor for picolinic acid derivatives and vitamin precursors. It maintains a high technical grade assay to meet the rigorous purity standards of fine chemical manufacturing.
The product is essential for the production of herbicides and fungicides, offering superior reactivity in nitrile hydrolysis processes. It is valued for its role in creating metal-chelating agents and specialized ligands for industrial catalysis.
Typical Properties
| Molecular formula | C6H4N2 |
|---|---|
| Molecular weight | 104.11 g/mol |
| Form | Low Melting Crystalline Solid |
| Color | White to brown |
| Melting point | 29 °C |
| Boiling point | 224.5 °C |
| Density | 1.0810 g/cm³ @ Temp: 25 °C |
| Water solubility | immiscible |
| Flash point | 193 °F |
| pH | 8.4 (100g/l, H2O) |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29333999 |
| Grades available | Technical Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
2-cyanopyridine
Applications
- Pharmaceutical Synthesis: Acts as a key building block for the production of picolinate-based APIs and various neuro-active pharmaceutical ingredients.
- Agrochemical Manufacturing: Utilized in the formulation of high-performance herbicides and pesticides, serving as a functionalized pyridine intermediate.
- Vitamin Production: Serves as a vital chemical precursor in the industrial synthesis of Vitamin B3 (Niacin) and related nutritional food additives.
Safety & Risks
This compound is toxic if swallowed and poses a risk of acute dermal toxicity. It is classified as a serious eye irritant and skin sensitizer. Handling requires nitrile gloves, chemical safety goggles, and NIOSH-approved respirators within a well-ventilated fume hood.
Packaging
• 1 kg / 5 kg Aluminum Foil Bags (for specialty/lab use)
• 25 kg Fiber Drums with internal PE liners (standard industrial format)