2-Acetylthiophene

2-Thienyl methyl ketone, Methyl 2-thienyl ketone, 1-(2-thienyl)ethanone.

CAS
88-15-3
EC
201-804-6
Sectors
Pharma & Healthcare, Agriculture, Food & Nutrition
2-Acetylthiophene is an aromatic ketone that serves as a cornerstone for the synthesis of bioactive molecules. It is a Technical Grade intermediate prized for its purity and predictable reactivity in condensation reactions. This compound is widely used in the production of thienyl-based pharmaceuticals. It provides a reactive acetyl group that is essential for forming complex heterocyclic rings in drug development. In the flavor and fragrance industry, it is utilized as a Specialty Chemical to provide specific roasted or nutty notes. Its high chemical stability makes it a reliable precursor for both fine chemicals and agrochemicals.

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2-Acetylthiophene

Applications
  • API Manufacturing: Used in the synthesis of Duloxetine and various other medications for neurological disorders.
  • Crop Protection: Serves as a precursor for specialty herbicides that require specific heterocyclic structural motifs.
  • Fragrance Chemistry: Employed as an intermediate to create unique aroma chemicals for industrial applications.
Safety & Risks
Classified as Acute Toxic (Category 3) and Combustible Liquid. It is Harmful to aquatic life. Wear Chemical-resistant Clothing, Respirators, and Gloves during transfer.
Packaging

25 kg Plastic Pails, 200 kg Steel Drums, or 1000 kg IBC Tanks.