Quinine HYDROCHLORIDE
Quinine HCl, Quinine Chloride, Chininum Muriaticum
- CAS
- 130-89-2
- EC
- 205-001-1
- Sectors
- Pharma & Healthcare, Food & Nutrition
Quinine Hydrochloride (CAS 130-89-2) is an alkaloid salt derived from Cinchona tree bark, supplied as a white crystalline powder, and used as a pharmaceutical active ingredient for malaria treatment and as a regulated bittering agent in tonic water and other soft drinks. It is primarily valued for its antimalarial properties and its clinical efficacy as a skeletal muscle relaxant in specialized medical formulations.
In the global food and beverage sector, this compound is the industry-standard bittering agent used to create the distinct organoleptic profile of tonic water and bitter mixers. Its excellent solubility in aqueous solutions and consistent purity levels make it ideal for high-speed industrial bottling and flavor concentrate production.
Available as a crystalline white powder, it meets rigorous USP/BP/EP pharmacopoeia standards, ensuring safety and compliance for sensitive applications. Beyond its primary roles, it serves as a sophisticated chiral resolving agent in organic chemistry and advanced laboratory synthesis processes.
Typical Properties
| Molecular formula | C20H24N2O2.ClH |
|---|---|
| Molecular weight | 360.88 g/mol |
| Form | Solid |
| Color | White |
| Melting point | 159 °C |
| Water solubility | 549.7mg/L(25 °C) |
| GHS signal word | Warning · Irritant / harmful, Health hazard |
| HS code | 29392000 |
| Grades available | Pharma Grade, Food Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Quinine HYDROCHLORIDE
Applications
- Antimalarial Medication: Functions as a vital API in the production of pharmaceutical treatments for chloroquine-resistant malaria and babesiosis.
- Beverage Bitters: Employed as a regulated flavor additive in the soft drink industry to provide the characteristic sharp taste of tonic waters.
- Therapeutic Muscle Relaxants: Integrated into medicinal products targeted at the treatment of nocturnal leg cramps and associated muscular spasms.
Safety & Risks
Quinine Hydrochloride is classified as Harmful if Swallowed and may cause Skin Sensitization or severe eye irritation. All industrial handling must include Chemical Resistant Gloves, Safety Goggles, and Protective Clothing to prevent direct contact and respiratory exposure.
Packaging
- 1 kg / 5 kg Aluminum Foil Bags
- 25 kg Cardboard Drums with double PE inner liners