Sodium Iodide
NaI, Sodium Iodine.
- CAS
- 7681-82-5
- EC
- 231-679-3
- Sectors
- Pharma & Healthcare, Electronics & Solar PV
Sodium Iodide (CAS 7681-82-5) is a highly soluble inorganic salt supplied as white crystalline beads, valued as a primary iodide source at purity above 99% for radiopharmaceutical precursors, scintillation detector crystals, and pharmaceutical synthesis. It is a primary source of iodide ions, valued for its high purity (>99%) and its specific ability to act as a precursor in medical imaging and radiopharmaceuticals.
This compound exhibits unique optical properties, making it a critical material for scintillation detectors, where it is doped with thallium to detect gamma radiation. Its hygroscopic nature requires careful storage to maintain its integrity for high-precision analytical applications.
In clinical settings, it is utilized as an expectorant and a nutritional supplement to prevent iodine deficiency. Its high water solubility and compatibility with organic solvents like ethanol make it a versatile reagent for the Finkelstein reaction in specialty organic synthesis.
Typical Properties
| Molecular formula | INa |
|---|---|
| Molecular weight | 149.89 g/mol |
| Appearance | Crystalline |
| Form | beads |
| Color | White |
| Melting point | 651 °C |
| Boiling point | 1304 °C |
| Density | 3.67 g/cm³ |
| Water solubility | 184 g/100 mL (25 °C) |
| Flash point | 1300-1304°C |
| pH | 6-9 (50g/l, H2O, 20°C) |
| GHS signal word | Danger · Irritant / harmful, Health hazard, Environmental hazard |
| HS code | 28276000 |
| Grades available | Pharma Grade, Electronic Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Sodium Iodide
Applications
- Medical Imaging: Used as a contrast agent and in the production of radioactive iodine (I-131) for thyroid diagnosis and therapy.
- Radiation Detection: Employed in the manufacture of scintillation crystals for X-ray and gamma-ray spectroscopy in security and medical fields.
- Organic Synthesis: Functions as a catalyst and iodide source in the synthesis of pharmaceuticals and fine chemicals through nucleophilic substitution.
Safety & Risks
Classified as STOT RE 1 (Thyroid) and Aquatic Acute 1. Prolonged exposure can affect thyroid function; handle with Gloves and Safety Glasses in controlled laboratory settings.
Packaging
1 kg Sealed Bottles, 25 kg Fiber Drums, and specialized vacuum-sealed containers.