Vitamin B9 L-Methylfolate Calcium
Calcium L Methyl Tetrahydrofolate, L-5-MTHF-Ca, Levomefolate Calcium, Metafolin
- CAS
- 151533-22-1
- EC
- 604-798-6
- Sectors
- Nutraceuticals & Supplements, Pharma & Healthcare, Food & Nutrition
Vitamin B9 L-Methylfolate Calcium (CAS 151533-22-1) is the biologically active and stable form of folate, supplied as an off-white to light yellow crystalline powder that bypasses enzymatic conversion, acts as a methyl donor for DNA synthesis and cardiovascular support, and is used mainly in prenatal vitamins and folate-deficiency supplements. This Pharma/USP Grade active provides superior bioavailability compared to synthetic folic acid.
The product is a High Purity crystalline powder that bypasses the body's enzymatic conversion steps, making it ideal for medical foods. It serves as a critical methyl donor for DNA synthesis and cardiovascular health support.
Commercially, it is the preferred active for prenatal vitamins and supplements targeting folate deficiency. Its excellent stability in solid dosage forms ensures high performance in professional-grade nutraceutical manufacturing.
Vitamin B9 L-Methylfolate Calcium is available from SoleChem as Pharma Grade material in 1 kg aluminum foil bags or 25 kg fiber drums. SoleChem stocks this Pharma Grade folate active for nutraceutical, pharmaceutical and food customers, and deliveries reach more than 40 countries.
The material is held under ISO 9001:2015 and ISO 22000:2018 quality systems, the latter covering food and nutraceutical products. A certificate of analysis (COA) and a safety data sheet (SDS) accompany every delivery. Send your target quantity and required specification to request a bulk quote.
Typical Properties
| Molecular formula | C40H48CaN14O12 |
|---|---|
| Molecular weight | 956.974 g/mol |
| Form | Solid |
| Color | Off-White to Light Yellow |
| Odor | at 100.00?%. odorless |
| Melting point | >300°C |
| GHS signal word | Warning · Irritant / harmful |
| HS code | 29339900 |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Applications by Industry
- Nutraceuticals & Supplements
Vitamin B9 L-Methylfolate Calcium serves supplement formulators as the primary bioactive folate source for prenatal vitamins, mood support and heart health capsules.
- Pharma & Healthcare
Vitamin B9 L-Methylfolate Calcium is used in prescription-grade pharmaceutical drugs for treating hyperhomocysteinemia and folate malabsorption.
- Food & Nutrition
Vitamin B9 L-Methylfolate Calcium supports fortified food and beverage applications, including specialized medical nutrition and infant formulas that require reliable folate absorption.
Vitamin B9 L-Methylfolate Calcium
Applications
- Nutritional Supplements: Primary bioactive folate source for prenatal vitamins, mood support, and heart health capsules.
- Fortified Food & Beverage: Used in specialized medical nutrition and infant formulas to ensure reliable folate absorption.
- Pharmaceutical Drugs: Formulated in prescription-grade medications for treating hyperhomocysteinemia and folate malabsorption.
Safety & Risks
Generally considered Non-Hazardous; handle as a high-purity nutritional active. Use Standard Lab PPE, including gloves and dust masks, to maintain a sterile handling environment.
Packaging
1 kg Aluminum Foil Bags or 25 kg Fiber Drums.