Vitamin B5 Panthenyl Ethyl Ether

Panthenyl ethyl ether, (+)-N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutyramide, F4WMF8NX3B, ORISTAR PEE

CAS
667-83-4
EC
211-569-1
Sectors
Personal Care & Cosmetics, Pharma & Healthcare

Vitamin B5 Panthenyl Ethyl Ether (CAS 667-83-4) is the ethyl ether of panthenol, a lipophilic provitamin B5 derivative that appears as a clear to slightly yellowish liquid, penetrates lipid-rich skin and hair structures more readily than standard panthenol, and acts as a moisturizing and conditioning active in topical formulations. Supplied as a clear to slightly yellowish liquid, it has a density of 1.073 g/mL at 20 °C, boiling point 443.8 °C (predicted), and flash point 110 °C.

The ethyl ether modification of panthenol increases lipophilicity, enhancing penetration through lipid-rich skin and hair structures compared to standard panthenol. It functions primarily as a moisturising and conditioning active in topical cosmetic and pharmaceutical formulations.

Vitamin B5 Panthenyl Ethyl Ether ships from SoleChem stock in two grades, Food Grade and Pharma Grade. Both grades are supplied in drums and small-lot containers for formulators and buyers in Personal Care & Cosmetics and Pharma & Healthcare, and every delivery includes a certificate of analysis (COA) and safety data sheet (SDS).

SoleChem holds ISO 9001:2015 certification and arranges deliveries to more than 40 countries. Share the grade, volume and packaging format you require, and SoleChem will respond with a bulk quote.

Typical Properties

Molecular formulaC11H23NO4
Molecular weight233.3 g/mol
Density1.073 g/mL at 20 °C
Flash point110 °C
Grades availableFood Grade, Pharma Grade

Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.

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Applications by Industry

  • Personal Care & Cosmetics

    Vitamin B5 Panthenyl Ethyl Ether serves personal care formulators in serums, creams and lotions for skin hydration and barrier support, and in conditioners that improve deposition on the hair shaft.

  • Pharma & Healthcare

    Vitamin B5 Panthenyl Ethyl Ether is used in Pharma Grade dermal preparations that need provitamin B5 with deeper skin penetration, and in controlled-purity topical pharmaceutical applications.

Vitamin B5 Panthenyl Ethyl Ether

Applications
  • Personal Care & Cosmetics: serums, creams, lotions for skin hydration and barrier support
  • Hair Care: conditioners improving deposition on hair shaft, reducing moisture loss
  • Sun Care: after-sun products for moisture retention post-environmental exposure
  • Topical Pharmaceuticals: dermal preparations needing provitamin B5 with deeper skin penetration
  • Pharma & Healthcare: Pharma Grade spec for controlled-purity provitamin B5 applications
Safety & Risks

Not classified as hazardous under GHS. Flash point 110 °C; handle away from ignition sources. Use standard PPE. Store in sealed containers, away from heat and direct light.

Packaging

Supplied in drums and small-lot containers; Food Grade and Pharma Grade available. Store sealed, cool, and away from direct light.