Vitamin B5 Panthenyl Ethyl Ether

Panthenyl ethyl ether, (+)-N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutyramide, F4WMF8NX3B, ORISTAR PEE

CAS
667-83-4
EC
211-569-1
Sectors
Personal Care & Cosmetics, Pharma & Healthcare

Vitamin B5 Panthenyl Ethyl Ether (CAS 667-83-4) is the ethyl ether of panthenol, a lipophilic provitamin B5 derivative that appears as a clear to slightly yellowish liquid, penetrates lipid-rich skin and hair structures more readily than standard panthenol, and acts as a moisturizing and conditioning active in topical formulations. Supplied as a clear to slightly yellowish liquid, it has a density of 1.073 g/mL at 20 °C, boiling point 443.8 °C (predicted), and flash point 110 °C.

The ethyl ether modification of panthenol increases lipophilicity, enhancing penetration through lipid-rich skin and hair structures compared to standard panthenol. It functions primarily as a moisturising and conditioning active in topical cosmetic and pharmaceutical formulations.

Typical Properties

Molecular formulaC11H23NO4
Molecular weight233.3 g/mol
Density1.073 g/mL at 20 °C
Flash point110 °C
Grades availableFood Grade, Pharma Grade

Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.

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Vitamin B5 Panthenyl Ethyl Ether

Applications
  • Personal Care & Cosmetics: serums, creams, lotions for skin hydration and barrier support
  • Hair Care: conditioners improving deposition on hair shaft, reducing moisture loss
  • Sun Care: after-sun products for moisture retention post-environmental exposure
  • Topical Pharmaceuticals: dermal preparations needing provitamin B5 with deeper skin penetration
  • Pharma & Healthcare: Pharma Grade spec for controlled-purity provitamin B5 applications
Safety & Risks

Not classified as hazardous under GHS. Flash point 110 °C; handle away from ignition sources. Use standard PPE. Store in sealed containers, away from heat and direct light.

Packaging

Supplied in drums and small-lot containers; Food Grade and Pharma Grade available. Store sealed, cool, and away from direct light.