Salcaprozate Sodium
SNAC, Sodium 8-[(2-hydroxybenzoyl)amino]octanoate.
- CAS
- 203787-91-1
- EC
- 682-351-1
- Sectors
- Pharma & Healthcare
Salcaprozate Sodium (CAS 203787-91-1) is a Pharmaceutical Grade absorption enhancer supplied as a white to off-white solid that raises the lipophilicity of water-soluble drugs through non-covalent complexation, improving the oral bioavailability of therapeutic peptides, proteins and other poorly permeable actives. It is a key functional excipient used to facilitate the oral delivery of poorly permeable drugs and macromolecules. This mechanism significantly improves the bioavailability of therapeutic peptides and proteins. This compound is recognized for its excellent safety profile and is widely utilized in innovative drug delivery systems (DDS). It remains stable under standard pharmaceutical manufacturing conditions and storage protocols.
Typical Properties
| Molecular formula | C15H21NO4.Na |
|---|---|
| Molecular weight | 301.313 g/mol |
| Form | Solid |
| Color | White to Off-White |
| Melting point | 183 - 185°C |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Salcaprozate Sodium
Applications
- Oral Peptide Delivery: Essential for the oral formulation of GLP-1 agonists and other peptide-based medications.
- Bioavailability Enhancement: Used to increase the intestinal absorption of vitamins and heparin-based anticoagulants.
- Drug Formulation: Serves as a specialized carrier in solid dosage forms to overcome the gastric acid barrier.
Safety & Risks
Regulated as a Low Hazard pharmaceutical intermediate. Use Respirators and Lab Coats in cleanroom environments to prevent cross-contamination.
Packaging
1 kg / 5 kg Aluminum Foil Bags or 25 kg Fiber Drums for commercial production.