Amoxicillin Trihydrate
Amoxycillin Trihydrate, p-Hydroxyampicillin, AMX
- CAS
- 61336-70-7
- EC
- 612-127-4
- Sectors
- Pharma & Healthcare, Animal Nutrition
Amoxicillin Trihydrate (CAS 61336-70-7) is a semi-synthetic, broad-spectrum beta-lactam antibiotic supplied as a white to off-white neat powder with a p-hydroxy-penicillin core, used as a Pharma Grade active ingredient in oral tablets, capsules and suspensions and in veterinary medicated feed and water-soluble powders. This USP/BP Grade active ingredient is critical for manufacturing stable oral dosage forms with high therapeutic purity.
The molecular structure features a p-hydroxy-penicillin core with a trihydrate crystal lattice, ensuring optimal chemical stability and solubility in aqueous environments. It is a cornerstone for producers requiring a high-purity API for consistent pharmaceutical performance.
In the commercial sector, it serves as a primary antibacterial agent for both human medicine and veterinary applications. Its proven safety profile and industrial reliability make it a global standard for treating diverse systemic and respiratory infections.
Typical Properties
| Molecular formula | C16H19N3O5S.3H2O |
|---|---|
| Molecular weight | 419.45 g/mol |
| Form | neat |
| Color | White to Off-White |
| Melting point | >200°C (dec.) |
| Water solubility | Soluble in water at 3.4mg/ml. |
| GHS signal word | Danger · Irritant / harmful, Health hazard, Environmental hazard |
| HS code | 29411099 |
| Grades available | Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Amoxicillin Trihydrate
Applications
- Human Pharmaceuticals: Used as the primary active pharmaceutical ingredient (API) in the production of tablets, capsules, and oral suspensions for systemic infections.
- Veterinary Formulations: Integrated into medicated feed and water-soluble powders to treat bacterial pathogens in livestock, poultry, and aquaculture.
- Laboratory R&D: Utilized as a reference standard in antimicrobial susceptibility testing and the development of novel combination therapies.
Safety & Risks
Classified as a Respiratory and Skin Sensitizer. Exposure may cause allergic reactions or asthma symptoms. Handling requires N95 respirators, chemical-resistant gloves, and protective goggles to ensure operator safety in production environments.
Packaging
- 25 kg Fiber Drums with inner PE liners
- 1 kg / 5 kg Aluminum Foil Bags for specialty batches