Vitamin B9 L-5-Methyltetrahydrofolate Glucosamine Salt
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- CAS
- 1181972-37-1
- Sectors
- Nutraceuticals & Supplements, Food & Nutrition
Vitamin B9 L-5-Methyltetrahydrofolate Glucosamine Salt (CAS 1181972-37-1) is the glucosamine salt form of (6S)-5-methyltetrahydrofolic acid, the biologically active reduced form of folate, presented as a fine crystalline powder with enhanced aqueous solubility, and used in food supplement and pharmaceutical formulations. Molecular formula C₂₆H₃₈N₈O₁₁, molecular weight 638.63 g/mol. As the metabolically active folate species, it bypasses hepatic conversion steps required by folic acid, making it the preferred folate source in food supplement and pharmaceutical formulations. Listed under Annex II of Directive 2002/46/EC as '(6S)-5-methyltetrahydrofolic acid, glucosamine salt', confirming its status as an authorised vitamin source for food supplements in the EU.
Typical Properties
| Molecular formula | C26H38N8O11 |
|---|---|
| Molecular weight | 638.627 g/mol |
| Grades available | Food Grade, Pharma Grade |
Typical literature values for identification; lot-specific results are stated on the certificate of analysis (COA) and the safety data sheet (SDS) that accompany every delivery.
Vitamin B9 L-5-Methyltetrahydrofolate Glucosamine Salt
Applications
- Nutraceuticals & Supplements: EU-authorised for maternal, immune, and homocysteine health claims
- Pharmaceutical: active ingredient targeting folate deficiency and homocysteine management
- Food & Nutrition: permitted in supplements; excluded from general food fortification
- Cosmetics: used in topical formulations seeking cellular folate activity
- Animal Feed & Veterinary: bioavailable folate for companion animal and livestock premixes
Safety & Risks
Not classified as hazardous under GHS. Handle with standard laboratory/industrial hygiene; avoid inhalation of dust. Use appropriate PPE including gloves and eye protection. No significant acute toxicity identified at typical handling quantities.
Packaging
Supplied in 25 kg fibre drums or cartons; 1 kg and 5 kg sealed bags available for small lots. Store cool, dry, and protected from light and moisture.